哮喘联盟

   摘要
   背景：哮喘急性发作是急性恶化的哮喘症状之一。急性发作可能与环境因素相关。
   目的：本研究调查了急救呼叫的哮喘急性加重儿童，分析1)整个过程的趋势,和2)他们与环境因素的关系，包括空中散布的花粉量，气象参数和空气污染。
   方法: 记录(2002-2011年)10年间意大利热那亚哮喘急性发作的紧急呼叫情况。测量桦木科、荨麻科、禾木科和木犀科空中散布的花粉量。也测量同一区域、同一时期的气象参数和空气污染物。
   结果：急救呼叫数量在研究期间没有很大的变动。检测到2个主要的高峰期：秋季和春季。风速显著地减少了大多数的空气污染物。急救呼叫与春季花粉(r=0.498)、降雨(r=0.818)、风速(r=0.727)以及空气污染物(r=0.622 for SO2; r=0.699 for NO; r=0.58 for NO2)具有显著相关性。
   结论：10年的研究证明了：(i)哮喘急性加重并没有减少；(ii)存在季节高峰期(秋天和春天)；(iii)花粉(主要是墙草属)，风速和降雨，SO2、NO、O3和NO2 与该区域哮喘急性加重儿童显著相关。因此，哮喘急性加重取决于环境条件的变化。
 

（苏楠 审校）
Allergol Immunopathol (Madr). 2013 Jun 4. pii: S0301-0546(13)00106-7. doi: 10.1016/j.aller.2013.02.006. [Epub ahead of print]

 

Asthma exacerbation in children: Relationship among pollens, weather, and air pollution.
 

Tosca MA, Ruffoni S, Canonica GW, Ciprandi G.
 

Abstract
BACKGROUND: Asthma exacerbation is an episode of (sub)acute worsening of asthmatic symptoms. Exacerbation may depend on environmental factors.
OBJECTIVE: The present study investigated emergency calls for asthma exacerbation in children, analysing: i) their trend over the course of time; and ii) their possible relationship with environmental factors, including pollen count, meteorological parameters, and air pollution.
METHODS: Emergency calls for exacerbation were recorded for 10 years (from 2002 to 2011) in Genoa (Italy). Betulaceae, Urticaceae, Gramineae, and Oleaceae pollen counts were measured. Meteorological parameters and air pollutants were also measured in the same area and for the same period.
RESULTS: The number of emergency calls did not significantly modify during the time studied. Two main peaks were detected: during the autumn and the spring. Wind speed significantly diminished as did most air pollutants. There were significant and relevant relationships between emergency calls and: pollens during the spring (r=0.498), rainfall (r=0.818), wind speed (r=0.727), and air pollutants (r=0.622 for SO2; r=0.699 for NO; r=0.58 for NO2).
CONCLUSIONS: This 10-year survey demonstrates that: (i) asthma exacerbations did not diminish over the time; (ii) there were seasonal peaks (autumn and spring); (iii) pollens (mainly Parietaria), wind speed and rainfall, SO2, NO, O3 and NO2 were strongly associated with asthma exacerbations in children in this area. Therefore, asthma exacerbations may significantly depend on environmental variations.
 

Allergol Immunopathol (Madr). 2013 Jun 4. pii: S0301-0546(13)00106-7. doi: 10.1016/j.aller.2013.02.006. [Epub ahead of print]